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Catalog Record: Toxicological profile for chromium | HathiTrust Digital Library
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Contact Dermatitis , 27 4 , Hansen, M. Contact Dermatitis , 49 4 , Plasma Cr concentration was recommended as a sensitive parameter, limited by its lack of specificity. This could potential be a non-invasive alternative to measure exposure to Cr VI compounds long after exposure. The above biomarkers of exposure are not sufficiently validated and great efforts could be made in this sense. In addition, while biomonitoring of occupationally exposed workers has been used to assess high-level inhalation exposures in the workplace, evaluating low-level environmental exposure to Cr VI has to be still addressed.
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Moreover, the inter- and intrapersonal variability in background levels of Cr is known to be significant and influenced by food and beverage intake, smoking, exercise, habits. Thus, the role of each factor must be carefully understood. Overview of the biomoritoring methods is available for total Cr in occupational setting. The DFG proposed two regulatory methods: the first for total Cr in urine, the second for total Cr in whole blood as well as in plasma and in erythrocytes.
However, several methods aiming at direct or indirect measurement of Cr VI have been published in literature. However, none of these methods have obtained the status of regulatory method yet nor have they undergone a validation. The current migration limits for Cr VI from toys are: 0. The exposure to chromium VI is mainly occupational. Hence, the policy questions reflect that but not only in order to have a wider picture of the exposure of the EU population.
Metabolic Toxicity and Alteration of Cellular Bioenergetics by Hexavalent Chromium
In the interest of transparency and accountability, HBM4EU invites interested stakeholders to submit comments on the scoping document. All submitted comments will be made available for download on this webpage and will be taken into consideration by the HBM4EU consortium, where possible. Please click here to submit your comments. Toxicological Profile for Chromium.
Blade, L. Hexavalent chromium exposures and exposure-control technologies in American enterprise: results of a NIOSH field research study. Costa, M. Toxicity and carcinogenicity of chromium compounds in humans. Crit Rev Toxicol. De Flora, S. Threshold mechanisms and site specificity in chromium VI. Bolt, J.
DOI: 0. Published online 31 Jan Retrieved 27 September, Page EH40 Second edition. Monographs on the Evaluation of Carcinogenic Risks to Humans. Chromium VI Compounds. INSHT National Institute for Occupational Safety and Health, Occupational Exposure to Hexavalent Chromium. Cincinnati, OH: U. NIOSH policy statements.
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Occupational Safety and Health Administration, Scientific Opinion of the Panel on Contaminants in the Food Chain on on the risks to public health related to the presence of chromium in food and drinking water. Stearns, D. Biochemistry 34, — Suzuki, Y. How does Europe PMC derive its citations network? Protein Interactions.
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